Weekly Chest CasesCases by Disease Category

Case No : 893 Date 2014-12-08

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  • Courtesy of Gong Yong Jin / Chonbuk National University Medical School and Hospital
  • Age/Sex 47 / M
  • Chief ComplaintDyspnea (Onset: 2 hours later after cleaning up a greenhouse), No fever
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initial chest PA

Diagnosis With Brief Discussion

Diagnosis
Chemical pneumonitis induced by nitric acid inhalation
Radiologic Findings
There is ground glass opacity with multifocal nodular opacity in both lungs on chest X-ray. On chest CT, multifocal patchy consolidation with bilateral diffuse ground glass opacity was shown. There is no pleural effusion.
Brief Review
He is a cleaning man and cleaned up greenhouse during 1 hour after 60% HNO3 spillage. Chemical pneumonitis usually occurs after occupational exposure and inhalation of various noxious gases, fumes and chemical compounds. However, chemical pneumonitis induced by nitric acid inhalation is a rare.
The chest X-ray showed multifocal patchy consolidation and diffuse interstitial opacities on whole lung fields. CT findings of this disease include bilateral perihilar consolidation and ground-glass attenuation, suggesting acute alveolar injury, delayed bronchiolitis obliterans, and bronchiectasis. Eighth days later after conservative management that included an oxygen supply with steroid therapy in the intensive care unit, his symptoms were improved and the hypoxemia was corrected. At the 8th day, the chest radiograph became normal.
References
1. White CS, Templeton PA. Chemical pneumonitis. Radiol Clin
North Am 1992;30:1231-1243
2. McLoud TC. Occupational lung disease. Radiol Clin North Am
1991;29:931-941
Keywords
Lung, Inhalation and aspiration disease,

No. of Applicants : 79

▶ Correct Answer : 2/79,  2.5%
  • - National Hospital Organization Okinawa Hospital , Japan Yasuji Oshiro
  • - The University of Tokyo Hospital , Japan Takeyuki Watadani
▶ Correct Answer as Differential Diagnosis : 12/79,  15.2%
  • - The University of Tokyo Hospital , Japan Akifumi Hagiwara
  • - Kyoto University , Japan Akihiko Sakata
  • - The University of Tokyo Hospital , Japan Toshihiro Furuta
  • - Ondokuz Mayis University , Turkey Cetin Celenk
  • - Niigata City General Hospital , Japan Takao Kiguchi
  • - Kyung Hee University Hospital at Gangdong , Korea (South) Seong Jong Yun
  • - Asan Medical Center, Ulsan University , Korea (South) Mi Young Kim
  • - Asan medical center , Korea (South) Sang Young Oh
  • - Onomichi municipal hospital , Japan Hirofumi Mifune
  • - IRSA La Rochelle , France Denis Chabassiere
  • - Seirei Hamamatsu General Hospital , Japan Kenichi Mizuki
  • - Medicheck health care , Korea (South) Chae Lim
▶ Semi-Correct Answer : 1/79,  1.3%
  • - Saint Malo , France jean-baptiste Noel
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